Searchable abstracts of presentations at key conferences in endocrinology

ea0020p537 | Growth and Developmental Endocrinology | ECE2009

The effect of gestational hypothyroidism on insulin secretion from isolated islets of adult offspring in male rats

Zahedi-Asl Saleh , Farahani Hamid , Ghasemi Asghar , Faraji Farzaneh , Manaheji Homa

Introduction: Any abnormalities during pregnancy can affect the growth and development of the fetus and may have a long lasting effect presented during adulthood (intrauterine programming). In this study, the effect of maternal hypothyroidism on insulin secretion from the isolated islets of offspring has been investigated in male rats.Materials and methods: In Test group maternal hypothyroidism was induced using 0.02% propylthiouracyl in drinking water t...